DRMTLGY Peptide Night Cream Reviews: The Ultimate Hydrating Bedtime Formula

DRMTLGY Peptide Night Cream is an enriching, hydrating anti-aging formula that can eliminate dry, dull skin & smooth wrinkles and fine lines on the complexion.
By Jenn Sinrich - Updated December 15, 2022

Introduction – DRMTLGY Peptide Night Cream

As one of the top night creams on the market today, this formula contains rich moisture that your skin drinks in as you sleep at night.

DRMTLGY Peptide Night Cream promises to eliminate dry, dull, flaky skin, improve texture, and it has peptides which boost collagen, tightening and smoothing fine lines and wrinkles overnight.

Both developed by dermatologists and highly touted by may others, this formula is the ultimate anti-aging night cream. I use this Drmtlgy product myself on a regular basis and love the incredible before and after that I get from this night cream with a rich peptide base.

About the Brand – DRMTLGY

The manufacturer is a Los Angeles, California-based skin-care company called Drmtlgy. Founded in 2017, they offer a line of enriching products which include medical-grade organically-sourced ingredients.

Overview – Peptide Night Cream

Drmtlgy Peptide Night Cream

  • Form:Cream
  • Skin Type:All Skin Type
  • Benefit:Improve Texture and Firmness, Reduces Wrinkles and Fine Lines
  • Ingredients:Peptides, Allantoin, Cholesterol, Ceramides, Vitamin E
  • Brand:DRMTLGY
  • Weight:2.1 OZ.


  • The cream can lift and firm the skin.
  • It rejuvenates dry, dull skin.
  • This cream can protect the complexion from UV rays and harmful bacteria.
  • This product can smooth wrinkles and fine lines.
  • It can enhance skin texture.


  • There are no free product samples available.
  • Different users will have somewhat different results.
  • This is a popular cream that may sometimes run low on stock.

Key Ingredients

  • Peptides
  • Allantoin
  • Shea Butter
  • Cholesterol
  • Ceramides
  • Vitamin E

Brand Features

  • Suitable for all Skin Types.
  • Follows GMP Standards.
  • Cruelty-Free Brand, Free of Parabens, Sulfates, Gluten, and Fragrance.
  • 100% Organic
For more details, please visit the Official Website

What is the Science of drmtlgy Peptide Night Cream?

This peptide night cream draws a huge amount of liquid, which moisturizes deeply and boosts dry, dull skin. It also plumps the complexion which can smooth wrinkles and fine lines on the surface.

Some of the ingredients help to form a protective barrier that prevents moisture loss and stops harmful microbes from entering.

Given that its high in peptides, the cream stimulates collagen production. This tightens the skin, improves elasticity, and further smooths lines. An article in the International Journal of Recent Technology and Engineering discussed anti-aging cosmetics containing peptides [1].

The cream is high in anti-inflammatory agents which can lessen redness and swelling on the skin and may help heal skin conditions. It contains antioxidants which can get rid of free radicals and lower oxidative stress.

This can heal and repair the skin and protect from UV rays and other environmental agents. An article in ISRN Dermatology explored the role of antioxidants in preventing photoaging [2].

DRMTLGY Peptide Night Cream

DRMTLGY Peptide Night Cream

Ingredients in Peptide Night Cream

Drmtlgy’s peptide night cream contains some of the active ingredients as follows:

  • Shea Butter
  • This is a fatty, hydrating substance which comes from the African Shea Tree. It offers hydration and is also very healing and soothing to the complexion. It’s a potent emollient which can soften the skin as well as repair damage.

    Shea butter can heal conditions like eczema. An article in the International Journal of Molecular Science noted the high antioxidant and anti-inflammatory benefits of shea butter [3].

  • Peptides
  • These amino acids stimulate collagen and elastin, which tends to deplete as we get older. The added proteins tighten the skin and promote elasticity, smoothing wrinkles and lines. Peptides also provide moisture, and can help to get rid of dry, flaking skin, overall improves your beauty.

    They have antioxidant potential, repair skin damage, and help boost skin immunity. An article in the Journal of Cosmetic Dermatology examined the role of peptides, proteins, and growth factors in promoting healthy skin [4].

  • Vitamin E
  • One of the most powerful ingredients in skin care, this nutrient is a potent antioxidant which can repair damage to the skin and protect from harmful UV rays. Its anti-inflammatory properties can treat skin conditions like atopic dermatitis effectively.

    It can also improve blood flow by increasing the width of the blood vessels, promoting a healthier, more radiant complexion. The Linus Pauling Institute discussed Vitamin E and its benefits to skin health [5].

  • Allantoin
  • Derived from the Comfrey plant, this compound is very hydrating, and serves as an excellent moisturizer. In addition, it has powerful anti-inflammatory agents which can decrease swelling and redness and even treat wounds and burns.

    Its quite safe for every skin type, including sensitive. An article in Science Direct discussed the characteristics and properties of allantoin, including its benefits for the skin [6].

How Do the DRMTLGY Night Cream Features Rate?

Feature Rating
Ingredients 5/5
Safety 4.9/5
Benefits 4.9/5
Value For Cost 5/5
Return Policy 4.9/5
For more details, please visit the Official Website

Drmtlgy Peptide Night Cream Review

Frequently Asked Questions

Que: Who Should Use This Peptide Night Cream?

Ans: Drmtlgy night cream with collagen peptide is suitable for anyone with dull, dry skin, or wrinkles and lines that they want to eliminate. It’s also great for women with normal skin who want to slow aging and keep up the hydration of their complexion.

Que: Is This Night Cream Cruelty-Free?

Ans: Yes, this company is completely cruelty-free. They promise to never test their skin care products on animals, nor will they work with associates or suppliers who do.

Que: Where to Buy Drmtlgy Night Cream?

Ans: This peptide-based product is for sale on the manufacturer’s official website, and you can also buy it from other online retailers including Amazon.

On the official site, you have the option of making a one-time purchase for $46, or subscribing to the monthly service and paying $37. Click on the link at the top of the site and you’ll get an extra 20% savings sent to your phone.

Que: What is the Return Policy?

Ans: The manufacturer, Drmtlgy LLC, is offering a lengthy a 60-day return policy. If you are not happy with Peptide Night Cream, call or e-mail the company and then return the item within 60 days of the purchase date. You should get a full refund, minus the shipping.

Que: Does Drmtlgy Peptide Night Repair Cream Really Work?

Ans: This enriching night cream does work well, and this was clear from the drmtlgy’s Peptide Night Cream customer reviews that I read. This is not surprising, as the formula is incredibly rich and should be effective. I must agree that I use it myself every night, and it’s my favorite cream.

Que: How is Peptides Night Cream Unique From the Competition?

Ans: This is a powerful night formula which has a list of ingredients backed by science and research, and a team of dermatologists and other skin care experts develop it. It’s much more powerful than many other brands available.

Que: What Does DRMTLGY Peptide Night Cream Do?

Ans: DRMTLGY – Peptide Night Cream is a luxurious, creamy nighttime moisturizer that adds layers of hydration to help soften the appearance of aging and heal damaged skin. Peptides, ceramide, and antioxidants help reduce the appearance of lines, wrinkles, and sun damage, leaving skin looking enhanced and moisturised. 

Que: Do Peptides Reduce Wrinkles?

Ans: Different peptides provide different benefits. Neuropeptides relax facial muscles, resulting in fewer fine lines and wrinkles. They may even help to remove stretch marks, age spots, scars, and other skin problems.

Feature Vs Products Drmtlgy Peptide Night Cream Skinfix Peptide Cream Drunk Elephant Moisturizer
BRAND Drmtlgy Skinfix Barrier+ Drunk Elephant
INGREDIENTS Peptides, Allantoin, Cholesterol, Ceramides, Vitamin E Hydrating Triple Lipid Complex, Glycerin, Shea Butter Peptide Complex, Pygmy Waterlily Stem Cell Extract, Soybean Folic Acid Ferment Extract
BENEFITS Improve Texture and Firmness, Reduces Wrinkles and Fine Lines Visibly Brightens, Firms, and Plumps Visibly Improve Skin‘s Tone, Texture, and Firmness
PRICE $47 $52 $68

Drmtlgy Peptide Night Cream Customer Reviews

After reading many of the Drmtlgy Peptide formula comments, I concluded that this night cream is among the most loved brands on the market. Based on this, I bought some myself and have been enjoying its benefits immensely.

Here are some of my favorite customer reviews, to give you an idea of what people are saying about the cream.

Best Day And Night Cream
The peptide cream is so moisturizing and light that I use it in the morning too! No fragrance, no stickiness! Love!

Nightly Obsession
I have been using this nightly and my skin is so happy when I wake up! Definitely a must for living in the hot, dry desert!

All I can say is WOW! I use this product day & night. You will not be disappointed. You’re welcome! Melissa

I love this cream. It works great and soaks in immediately. I love the way my skin feels after I apply it. Melanie

Final Verdict – Drmtlgy Peptide Night Cream Reviews

This rich formula by Drmtlgy, LLC lifts, tightens, and hydrates the complexion while you sleep, so over time you wake to skin that is smoother, softer, and with decreased dryness, lines, and wrinkles. Formulated by top dermatologists in the field, it includes an all-natural collection of scientifically-backed ingredients.

The Drmtlgy peptide night cream review postings were very enthusiastic about the product and its rich skin benefits. This included feedback on reddit, Amazon, and other independent sites as well as on the official site. Most customers loved the hydrating and anti-aging benefits, and said they were using it regularly.

This luxurious drmtlgy peptide cream for night use is as organic as they come, with no chemical or artificial additives, fragrance, gluten, parabens, or sulfates. It should not lead to any side effects. I use it myself every night, and only have positive things to say.

Where To Find It?

For more details, please visit the Official Website

Customer Reviews for DRMTLGY Peptide Night Cream

DRMTLGY Peptide Night Cream Reviews: The Ultimate Hydrating Bedtime Formula
Reviewer Rating
4.9 / 5.0

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  1. Calissa N.

    Your Rating:

    Already Subscribed
    I love this Peptide Night Cream so much. I am almost finished my first bottle, and I am so happy with it that I just ordered a monthly subscription. Thank you so much!!!
  2. Sally G.

    Your Rating:

    Works Really Well
    A woman at work told me about this cream; her skin always looks fresh and young. It’s only been a couple of weeks, but I am so happy. I wake up with this glowing, moisturized skin which makes me feel good about myself. Terrific product.
  3. Joy

    Your Rating:

    Amazing Cream
    The Peptide Night Cream is a genuinely great skin care product. After using it for 2 months, I really feel like my appearance is better and I look younger. My complexion has a glow, is hydrated, and is smooth of some of the fine lines I had.
  4. Bea N.

    Your Rating:

    The Peptides Do the Job
    I have total faith in any cream which is rich in peptides, because I have found that they work really well to reverse the aging of your skin. Been using this one for a few weeks, and I am so happy with it. I would recommend it. – Bea N.
  5. Ben M.

    Your Rating:

    Best Night Cream
    This feels like a much more expensive cream, but the cost is really reasonable. I use it every night, and I wake with enriched, hydrated skin. It’s also really good at decreasing all of those smaller lines on your complexion. – Ben M.

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[1] A Clinical Evaluation of an Anti-Aging Cosmetics Containing Functional Peptides and an Epidermal Penetrating Peptide: https://www.ijrte.org/wp-content/uploads/papers/v7i6s5/F12160476S519.pdf
[2] Skin Photoaging and the Role of Antioxidants in Its Prevention: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789494/
[3] Anti-Inflammatory and Skin Barrier Repair Effects of Topical Application of Some Plant Oils: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5796020/
[4] Cosmeceuticals: Peptides, Proteins, And Growth Factors: https://onlinelibrary.wiley.com/doi/10.1111/jocd.12229
[5] Vitamin E and Skin Health: https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-E.
[6] Allantoin - An Overview | ScienceDirect Topics [7] https://www.cosmeticsandtoiletries.com/research/literature-data/article/21835355/Shea-Butter-Extract-for-Bioactive-Skin-Care
[8] Topical Peptide Treatments with Effective Anti-Aging Results: https://www.mdpi.com/2079-9284/4/2/16/htm
[9] Collagen Peptides Promote Photoaging Skin Cell Repair By Activating The TGF-?/Smad Pathway And Depressing Collagen Degradation:https://pubs.rsc.org/en/content/articlelanding/2019/fo/c9fo00610a [10] Vitamin E and Skin Health: https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-E
[11] The Structure, Function, And Importance Of Ceramides In Skin And Their Use As Therapeutic Agents In Skin-Care Products: https://pubmed.ncbi.nlm.nih.gov/24656726/